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Psychotherapy for Depression Alters Brain Chemistry

June 24, 2009

A research project, looking at chemical changes in the brains of patients with depression during their treatment with anti-depressants, has made an interesting finding. As a control group researchers tracked changes in the brain chemistry of patients with major depressive episodes who received  psychotherapy and no medication. Over six weeks, they found psychotherapy alone produced brain chemistry changes that formerly had been linked to administration of medication.

A group of German investigators demonstrated that the early increase in phosphorylated CREB pCREB is related to treatment response and does not depend on pharmacological interventions or brain-derived neurotrophic factor BDNF plasma levels. For the first time, cellular biological markers could be associated with response to psychotherapy.

via ScienceDaily (June 23, 2009)

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